Купить Characterisation of AMPK and Its Role in Mitochondrial Disease. ISBN 9783659809002.

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The AMPK heterotrimer comprised of a catalytic ? and regulatory non-catalytic ? and ? subunits acts as an intracellular energy sensor in eukaryotic cells. The AMPK ? subunit gene, snfA, is encoded by a single gene that is highly conserved with identical APE and DFG motifs. Overexpression of the truncated catalytic domain, AMPK ?380, caused dose dependant signalling defects, slow growth and prolonged generation times; a classical mitochondrial disease signs. AMPK sustained activation during.. описание на сайте интернет продавца